Erythrasma: successful treatment after single-dose clarithromycin A 31-year-old otherwise healthy African-American man

نویسندگان

  • Rym Benmously-Mlika
  • Wafa Koubaa
  • Achraf Debbiche
  • Insaf Mokhtar
چکیده

not available in our country, and surgery, in which recurrence rates after wide excision are lower than after local excision. Radiotherapy has been used only rarely for BD of the digit and has been delivered using various techniques (radioactive molds of gold or radon seeds, external beam therapy, photon radiotherapy using a water bath), as have laser carbon dioxide, photodynamic therapy, and topical 5-fluorouracil. However, recurrence rates vary from 0% to 50%. Only an eight-patient study tested the effectiveness of immunocryosurgery in the treatment of BD. Treatment consisted of the daily application of 5% imiquimod cream over three weeks, followed by cryosurgery (two freeze–thaw cycles, 10–20 seconds freezing time). Imiquimod was continued after cryosurgery, and patients were evaluated every three weeks. All lesions cleared completely within a six-month follow-up period. Only three patients required a second course of cryosurgery. In our case, we were unable to apply imiquimod cream prior to cryosurgery because of the delay imposed by the need to import it from Europe. Further studies using randomization and placebo control should be conducted to assess the added therapeutic effect of the association of imiquimod and cryosurgery in the management of digital BD.

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تاریخ انتشار 2013